COLUMBUS, Ohio – The Ohio State University
Wexner Medical Center
joins an elite network of 25 regional stroke centers announced today by the
National Institutes of Health (NIH) that will focus on prevention, treatment
and recovery. As part of the NIH Stroke Trials Network (NIH StrokeNet), Ohio
State will receive a 5-year, $2 million grant to develop a regional
coordinating stroke center.
“The primary goal of
this network is to maximize efficiencies to develop, promote and conduct
high-quality, multi-site clinical trials focused on key interventions in stroke
prevention, treatment and recovery,” said Dr. Michel Torbey, medical director of
Neurovascular Stroke Center. “Ohio State’s Comprehensive Stroke Center was selected
based on our clinical science excellence and specialized multidisciplinary
expertise in stroke management, a strong background in stroke research, and a proven
ability to recruit stroke patients.”
The regional stroke
centers will work with nearby satellite facilities across the country that have
teams of researchers representing every medical specialty needed for stroke
“The new system is
intended to streamline stroke research, by centralizing approval and review,
lessening time and costs of clinical trials, and assembling a comprehensive
data-sharing system,” said Dr. Petra Kaufmann, associate director for clinical
research at the National Institute of
Neurological Disorders and Stroke (NINDS).
NINDS, which will
fund and manage the NIH StrokeNet, has a strong history of successful stroke
clinical trials over the past 40 years, leading to advances in treatment and
prevention of the disease, including the first treatment for acute stroke,
announced in 1995. Stroke remains the number one cause of disability and fourth-leading
cause of death in the United States.
Ohio State’s Wexner
Medical Center will coordinate stroke clinical trials at its 24 telestroke
spoke hospitals, and at Mount Carmel Health System, University of Toledo and Wright
State University, said Torbey, who is also director of the Cerebrovascular and
Neurocritical Care Division.
The 25 centers selected
by the NIH are strategically placed in every region of the country. Successful
applicants demonstrated experience in stroke research and recruitment,
including the ability to enroll underrepresented populations. They also were
required to offer access to the full cadre of specialties that are involved in
stroke care, including emergency medicine, neurosurgery, interventional
neuroradiology, vascular neurology, neurointensive care, neuroimaging, stroke
rehabilitation and pediatric neurology.
Each center will receive
five-year funding, with $200,000 in research costs and $50,000 for training
stroke clinical researchers per year over the first three years, and additional
funds driven by the completion of milestones. The University of Cincinnati will
manage the national clinical coordinating center, which will oversee and
coordinate the institutional review board and master trial agreements for all
of the regional centers. NIH will announce the award of a national data
management center in February.
StrokeNet investigators, working with the broader stroke community, will
propose, develop and conduct stroke protocols to be administered within the
network and train the future generation of clinical researchers in stroke. The
network concept evolved from an NINDS planning effort in which stroke experts
were asked what is most needed to reduce death and disability due to stroke in
the United States. They called for a nationwide stroke network that would allow
for a more seamless transition between early safety and efficacy trials and
Phase II and III clinical trials.
stroke occurs when blood flow to the brain is interrupted, causing brain cells
in the immediate area to die because they stop getting oxygen. Stroke can also
occur when a vessel breaks and bleeds into the brain. The number of strokes
reported each year is 795,000. Because stroke is age-linked, the incidence is
expected to rise rapidly in the next decade.
this year, Ohio State’s Wexner Medical Center was recognized by The Joint
Commission and the American Heart Association/American Stroke Association as
meeting the Joint Commission’s standards for Comprehensive Stroke Center Certification.
Ohio State was one of the first 26 of the 900 primary stroke centers in the
United States to have received this award.
The Ohio State University Wexner Medical
Center Neuroscience Program features 160 researchers and clinicians
collaborating in neurology, neurosurgery, physical medicine and rehabilitation,
psychiatry and neuroscience research to create better methods of prevention,
detection and treatment.
For a high-quality photo of Dr. Michel Torbey,
Contact: Eileen Scahill, Wexner Medical Center
Public Affairs and Media Relations,
614-293-3737, or Eileen.Scahill@osumc.edu