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Carl Schmidt, MD

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Call us at 1-800-293-5123


Clinical Background & Robotic Expertise
Scholarly Publications
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Clinical Background and Robotic Expertise

Years in Practice: 4
Board Certified: Yes
Medical School: University of Michigan (Ann Arbor, MI)
Residency: Vanderbilt University Medical Center (Nashville, TN)
Robotics Training: Ohio State Center for Advanced Robotic Surgery (Columbus, OH)
Oncology Training: Memorial Sloan-Kettering Cancer Center (New York, NY)
Clinical Interests: Minimally-invasive surgery for liver, gastric, pancreatic and colorectal malignancies using robotic or laparoscopic techniques

Dr. Schmidt received his medical degree from the University of Michigan. His postgraduate training includes a general surgery residency at Vanderbilt University in Nashville, TN and a fellowship in surgical oncology at Memorial Sloan-Kettering Cancer Center in New York, NY. After joining the faculty at Ohio State, he was the first member of the Division of Surgical Oncology to undergo robotic training and to be credentialed for advanced robotic surgery.

Dr. Schmidt’s clinical research interests focus on the management of gastrointestinal malignancies including minimally-invasive thermal ablation therapy for liver cancers and laparoscopic and robotic operations for liver, pancreatic, gastric and colorectal cancers.

Relevant Awards

Ohio State College of Medicine Michael J. Walker Faculty Teaching Award, 2010
ASCO Foundation Merit Award (Gastrointestinal Cancers Symposium), 2008
Alfred Blalock Award for Most Significant Research Contributions, Vanderbilt University, 2006
ECOG-Aventis Young Investigator Award, 2004
Travel Award, 3rd Annual GI Cancers Symposium, University of St. Louis, 2004
Harvey Baker Traveling Fellow Award, Society of Surgical Oncology, 2004
Lloyd Rogers Award for Best Scientific Presentation, Association of VA Surgeons, 2003

Scholarly Publications

Klein RD, Su GL, Schmidt CR, Aminlari A, Steinstraesser L, Alarcon WH, Zhang HY, Wang SC. Lipopolysaccharide-binding protein accelerates and augments Escherichia coli phagocytosis by alveolar macrophages. Journal of Surgical Research 2000; 94: 159-66.

Schmidt CR, Washington MK, Gi YJ, Coffey RJ, Beauchamp RD, Pearson AS. Dysregulation of E-cadherin by oncogenic Ras in intestinal epithelial cells is blocked by inhibiting MAP kinase. American Journal of Surgery 2003; 186:426-30.

Schmidt CR, Gi YJ, Coffey RJ, Beauchamp RD, Pearson AS. Oncogenic Ras dominates overexpression of E-cadherin in malignant transformation. Surgery 2004; 136: 303-309.

Poulose BK, Scholz S, Moore DE, Schmidt CR, Grogan EL, Lao OB, Nanney L, Davidson J, Holzman MD. Physiologic properties of small intestine submucosa. Journal of Surgical Research 2005; 123: 262-7.

Dhawan P, Singh AB, Deane NG, No Y, Shiou SR, Schmidt C, Neff J, Washington MK, Beauchamp RD. Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. Journal of Clinical Investigation 2005; 115: 1765-1776.

Schmidt CR, Gi YJ, Patel TA, Coffey RJ, Beauchamp RD, Pearson AS. E-cadherin is regulated by the transcriptional repressor SLUG during Ras-mediated transformation of intestinal epithelial cells. Surgery 2005; 138: 306-12.

Johnson JC, Schmidt CR, Shrubsole MJ, Billheimer DD, Joshi PR, Morrow JD, Heslin MJ, Washington MK, Ness RM, Zheng W, Schwartz DA, Coffey RJ, Beauchamp RD, Merchant NB. Urine PGE-M: A metabolite of prostaglandin E2 as a potential bimarker of advanced colorectal neoplasia. Clinical Gastroenterology and Hepatology 2006; 4:1358-65.

Bennett JJ, Schmidt CR, Klimstra, DS, Grobmyer, SR, Ishill, NM, D’Angelica, MD, DeMatteo, RP, Fong, Y, Blumgart, LH, Jarnagin, WR. Perihepatic lymph node micrometastases impact outcome after partial hepatectomy for colorectal metastases. Annals of Surgical Oncology 2008; 15: 1130-6.

Kanies CL, Smith JJ, Kis C, Schmidt C, Levy S, Khabar KS, Morrow J, Deane N, Dixon DA, Beauchamp RD. Oncogenic Ras and Transforming Growth Factor-Beta Synergistically Regulate AU-Rich Element-Containing mRNAs During Epithelial to Mesenchymal Transition. Molecular Cancer Research 2008; 6:1124-36.

Schmidt C, Gerdes H, Hawkins W, Zucker E, Zhou Q, Riedel E, Jaques D, Markkowitz A, Coit D, Schattner M. A Prospective Observational Study Examining Quality of Life in Patients with Malignant Gastric Outlet Obstruction. Am J Surg 2009; 198:92-9.

Schmidt C, Panageas K, Coit D, Patel A, Brady M. An Increased Number of Sentinel Lymph Nodes is Associated with Advanced Breslow Depth and Lymphovascular Invasion in Patients with Primary Melanoma. Annals of Surgical Oncology 2009; 16: 948-52.

Smith JJ, Deane NG, Wu F, Merchant NB, Zhang B, Jiang A, Lu P, Johnson JC, Schmidt C, Edwards CM, Eschrich S, Kis C, Levy S, Washington MK, Heslin MJ, Coffey RJ, Yeatman TJ, Shyr Y, Beauchamp RD. Experimentally Derived Metastasis Gene Expression Profile Predicts Recurrence and Death in Patients With Colon Cancer. Gastroenterology 2009; 138: 958-68.

Hatzaras I, Schmidt C, Muscarella P, Melvin WS, Ellison EC, Bloomston M. Elevated CA 19-9 Portends Poor Prognosis in Patients Undergoing Resection of Biliary Malignancies. HPB 2010; 12: 134-8.

Abdel-Misih SR, Hatzaras I, Schmidt C, Saab TB, Klemanski D, Muscarella P, Melvin WS, Ellison EC, Bloomston M. Failure of Normalization of CA19-9 Following Resection for Pancreatic Cancer is Tantamount to Metastatic Disease. Ann Surg Oncol 2011; 18(4):1116-21.

Hatzaras I, Schmidt C, Klemanski D, Muscarella P, Melvin WS, Ellison EC, Bloomston M. Pancreatic Resection in the Octogenarian: A Safe Option for Pancreatic Malignancy. J Am Coll Surg 2011; 212(3):373-7

Mendel E, Mayerson JL, Nathoo N, Edgar RL, Schmidt C, Miller MJ. Reconstruction of the Pelvis and Lumbar-pelvic Junction using 2 Vascularized Autologous Bone Grafts after En Bloc Resection for an Iliosacral Chondrosarcoma. J Neurosurg Spine 2011; 15(2):168-73.

Chokshi RJ, Kuhrt MP, Schmidt C, Arrese D, Routt M, Parks L, Bahnson R, Martin EW Jr. Single Institution Experience Comparing Double-barreled Wet Colostomy to Ileal Conduit for Urinary and Fecal Diversion. Urology 2011 Oct;78(4):856-62.

Jones NB, McNally ME, Malhotra L, Abdel-Misih S, Martin EW, Bloomston M, Schmidt CR. Repeat Hepatectomy for Metastatic Colorectal Cancer Is Safe but Marginally Effective. Ann Surg Oncol 2011 Dec 30.

Schmidt CR, Shires P, Mootoo M. Real-time Ultrasound Imaging of Irreversible Electroporation in a Porcine Liver Model Adequately Characterizes the Zone of Cellular Necrosis. HPB 2012; 14(2):98-102.

McNally ME, Malhotra L, Bloomston M, Schmidt CR. Perioperative mortality in patients with myelodysplastic syndrome. J Surg Oncol 2012; Jan 9.

Schmidt CR. Learning the spirituality of life and medicine from others. Current Surgery, 2004; 5: 483-484.

Schmidt CR, Gollub MJ, Weiser MR. Contemporary imaging for colorectal cancer. Surgical Oncology Clinics of North America 2007; 16: 369-88.

Merchant N, Parikh A, Schmidt C, Beauchamp R. Cancer of the colon, rectum and anus. Textbook of Surgical Oncology. Informa Healthcare, London, UK 2007.

Abdel-Misih SR, Schmidt CR, Bloomston PM. Update and Review of the Multidisciplinary Management of Stage IV Colorectal Cancer with Liver Metastases. World Journal of Surgical Oncology 2009; 7: 72.

Marsh JW, Schmidt C. The Milan criteria: no room on the Metro for the king? Liver Transplantation 2010; 16:252-5.

Schmidt C, Marsh JW. Molecular Signature for HCC: Role in Predicting Outcomes after Liver Transplant and Selection for Potential Adjuvant Treatment. Current Opinion in Organ Transplant 2010; 15: 277-82.

Schmidt C, Bloomston M, Shah MH. Well-differentiated Neuroendocrine Tumors: a Review Covering Basic Principles to Loco-regional and Targeted Therapies. Oncogene 2011; 30: 1497-505.

Contact information

For more information about Dr. Schmidt and robotic surgery at Ohio State or to make an appointment to speak with one of our robotic surgery experts, please call us at 1-800-293–5123. Dr. Schmidt’s office number is 614-293-5644 and email carl.schmidt@osucm.edu.