Anderle P, Nielsen CU, Pinsonneault J, Krog PL, Brodin B, Sadee W. Genetic variants of the human dipeptide transporter PEPT1. J Pharmacol Exp Ther. 2006 Feb;316(2):636-46.
Besco JA, Hooft van Huijsduijnen R, Frostholm A, Rotter A. Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT).
Brain Res 2006 Oct 20;1116(1):50-7.
Biondi R, Ambrosio G, Liebgott T, Cardounel AJ, Bettini M, Tritto I, Zweier JL. Hydroxylation of D-phenylalanine as a novel approach to detect hydroxyl radicals: application to cardiac pathophysiology. Cardiovasc Res 2006 Jul 15;71(2):322-30.
Blower PE, Cross KP, Eichler GS, Myatt GJ, Weinstein JN, Yang C. Comparison of methods for sequential screening of large compound sets. Comb Chem High Throughput Screen 2006 Feb;9(2):115-22.
Blower PE, Cross KP. Decision tree methods in pharmaceutical research. Curr Top Med Chem 2006;6(1):31-9.
Bohn LM, Raehal KM. Opioid receptor signaling: relevance for gastrointestinal therapy.
Curr Opin Pharmacol 2006 Dec;6(6):559-63.
Chen R, Tilley MR, Wei H, Zhou F, Zhou FM, Ching S, Quan N, Stephens RL, Hill ER, Nottoli T, Han DD, Gu HH. Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter. Proc Natl Acad Sci USA 2006 Jun 13;103(24):9333-8.
Chen R, Wei H, Hill ER, Chen L, Jiang L, Han DD, Gu HH. Direct evidence that two cysteines in the dopamine transporter form a disulfide bond. Mol Cell Biochem 2006 Nov 25;
Chen R, Wu X, Wei H, Han DD, Gu HH. Molecular cloning and functional characterization of the dopamine transporter from Eloria noyesi, a caterpillar pest of cocaine-rich coca plants. Gene 2006 Jan 17;366(1):152-60.
Dai Z, Liu S, Marcucci G, Sadee W. 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer). Biochem Biophys Res Commun 2006 Dec 15;351(2):455-61.
Dai Z, Barbacioru C, Huang Y, Sadee W. Prediction of anticancer drug potency from expression of genes involved in growth factor signaling. Pharm Res 2006 Feb;23(2):336-49.
Ebihara T, Guo F, Zhang L, Kim JY, Saffen D. Muscarinic acetylcholine receptors stimulate Ca2+ influx in PC12D cells predominantly via activation of Ca2+ store-operated channels. J Biochem (Tokyo). 2006 Mar;139(3):449-58.
Groer CE, Tidgewell K, Moyer RA, Harding WW, Rothman RB, Prisinzano TE, Bohn LM. An opioid agonist that does not induce mu opioid receptor - arrestin interactions or receptor internalization. Mol Pharmacol 2007 Feb;71(2):549-57. [Epub 2006 Nov 7]
Gu HH, Wu X, Han DD. Conserved serine residues in serotonin transporter contribute to high-affinity cocaine binding. Biochem Biophys Res Commun 2006 May 19;343(4):1179-85.
Guzman J, Yu JG, Suntres Z, Bozarov A, Cooke H, Javed N, Auer H, Palatini J, Hassanain HH, Cardounel AJ, Javed A, Grants I, Wunderlich JE, Christofi FL. DOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis. Inflamm Bowel Dis 2006 Aug;12(8):766-89.
Han DD, Chen R, Hill ER, Tilley MR, Gu HH. Cause and solutions to the polymerase chain reaction smear problem in genotyping. Anal Biochem 2006 Jun 15;353(2):296-8.
Han DD, Gu HH. Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs. BMC Pharmacol 2006 Mar 3;6:6.
Huang Y, Sadee, W. Membrane transporters and channels in chemoresistance and -sensitivity of tumor cells. Cancer Lett. 2006 Aug 8;239(2):168-82.
Ilangovan G, Venkatakrishnan CD, Bratasz A, Osinbowale S, Cardounel AJ, Zweier JL, Kuppusamy P. Heat shock-induced attenuation of hydroxyl radical generation and mitochondrial aconitase activity in cardiac H9c2 cells. Am J Physiol Cell Physiol. 2006 Feb;290(2):C313-24.
Krejsa C, Rogge M, Sadee W. Protein therapeutics: new applications for pharmacogenetics. Nat Rev Drug Discov. 2006 Jun;5(6):507-21.
Li H, Liu X, Cui H, Chen YR, Cardounel AJ, Zweier JL. Characterization of the mechanism of cytochrome P450 reductase-cytochrome P450-mediated nitric oxide and nitrosothiol generation from organic nitrates. J Biol Chem 2006 May 5;281(18):12546-54.
Lim JE, Papp A, Pinsonneault J, Sadee W, Saffen D. Allelic expression of serotonin transporter (SERT) mRNA in human pons: lack of correlation with the polymorphism SERTPR. Molecular Psychiatry 2006 11:649-662.
Lucas JL, Wang D, Sadee W Calmodulin binding to peptides derived from the i3 loop of muscarinic receptors. Pharm Res 2006 Apr;23(4):647-53.
Nadolski G, Cardounel AJ, Zweier JL, Lockwood SF. The synthesis and aqueous superoxide anion scavenging of water-dispersible lutein esters. Bioorg Med Chem Lett. 2006 Feb 15;16(4):775-81.
Neff NH, Wemlinger TA, Duchemin AM, Hadjiconstantinou M. Clozapine modulates aromatic L-amino acid decarboxylase activity in mouse striatum. J Pharmacol Exp Ther 2006 May;317(2):480-7.
Pinsonneault JK, Papp AC, Sadee W. Allelic mRNA expression of X-linked monoamine oxidase a (MAOA) in human brain: dissection of epigenetic and genetic factors. Hum Mol Genet. 2006 Sep 1;15(17):2636-49.
Sadee W, Bohn L. How specific are "target-specific" drugs? Celecoxib as a case in point.
Mol Interv 2006 Aug;6(4):196-8.
Shah A, DeGroot T, Apseloff G. Pharmacokinetic evaluation and safety profile of a 15-minute versus 30-second infusion of palonosetron in healthy subjects.J Clin Pharmacol 2006 Oct;46(10):1139-45.
Vargo MA, Voss OH, Poustka F, Cardounel AJ, Grotewold E, Doseff AI. Apigenin-induced-apoptosis is mediated by the activation of PKCdelta and caspases in leukemia cells. Biochem Pharmacol 2006 Sep 14;72(6):681-92.
Venkatakrishnan CD, Tewari AK, Moldovan L, Cardounel AJ, Zweier JL, Kuppusamy P, Ilangovan G. Heat shock protects cardiac cells from doxorubicin-induced toxicity by activating p38 MAPK and phosphorylation of small heat shock protein 27. Am J Physiol Heart Circ Physiol 2006 Dec;291(6):H2680-91.
Wang D, Papp AC, Binkley PF, Johnson JA, Sadee W. Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissues. Pharmacogenet Genomics 2006 Oct;16(10):735-45
Wang D, Sadee W. Searching for polymorphisms that affect gene expression and mRNA processing: example ABCB1 (MDR1) AAPS J. 2006 Aug 18;8(3):E515-20.
Wang Y, Dai Z, Sadee W, Hancock WS. A pharmacoproteomics study of the cancer cell line EKVX using capillary-LC/MS/MS. Mol Pharm 2006 Sep-Oct;3(5):566-78.
Zhang L, Guo F, Kim JY, Saffen D. Muscarinic acetylcholine receptors activate TRPC6 channels in PC12D cells via Ca2+ store-independent mechanisms. J Biochem (Tokyo). 2006 Mar;139(3):459-70.